The typical American diet is loaded with foods that contain arachidonic acid (like egg yolk, red meat, poultry, and dairy products) or stimulate the production of excess arachidonic acid in the body (foods rich in high-glycemic carbohydrates, saturated fats, and omega-6 fatty acids).

Scientific studies show that, along with normal aging, excess arachidonic acid ignites a biochemical cascade that increases levels of the 5-lipoxygenase (5-LOX) enzyme, which can induce undesirable effects in cells throughout the body.* This cascade culminates in the excess accumulation of leukotriene B4, a proinflammatory compound that attacks the joints, the arterial wall, and other tissues.*

In India, extracts from the Boswellia plant have been used for centuries as anti-inflammatory agents.1 Recent human studies have confirmed that a specific Boswellia extract known as AKBA (3-O-acetyl-11 keto-ß-boswellic acid) selectively inhibits 5-LOX.2 Unlike other boswellic acids that only partially inhibit 5-LOX,2,3 AKBA binds directly to 5-LOX, effectively suppressing its pro-inflammatory activity.

5-LOXIN is a registered trademark of P.L. Thomas & Co., Inc. U.S. patents pending.