Life Extension, Mega GLA W/Sesame, 60 300 Mg Softgels

Life Extension, Mega GLA W/Sesame, 60 300 Mg Softgels
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Mega GLA with Sesame Lignans
60 softgels
Item Catalog Number: 756
This new formulation replaces: LEF-00218

Health conscious people have been consuming a lot of borage oil to obtain GLA (gamma-linolenic acid), the parent of the biologically active DGLA (di-homo-gamma-linolenic acid). Life Extension has added 10 milligrams of sesame lignans to each capsule of Mega GLA borage oil. Sesame lignans not only increase beneficial DGLA, but they also help control pro-inflammatory arachidonic acid, which decreases the formation of destructive prostaglandin E2 and leukotriene B4.1

Numerous studies document GLA’s multiple health effects, but new information about the ability of sesame to prevent the conversion of GLA into arachidonic acid indicates that many more people may now be able to benefit from supplemental GLA.2

1 Chavali SR, Zhong WW, Forse RA. Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL6, IL-10 in response to LPS: effects of sesamin on the delta-5-desaturatoin of omega-6 and omega-3 fatty acids in mice. Prostaglandins Leukot Essent Fatty Acids. 1998 Mar,58(3):185-91.
2. Umeda-Sawada R, Fujiware Y, Abe H, Seyama Y, Effects of sesamin and capsaicin on the mRNA expressions of delta-6- desaturases and delta-5-desaturases in rat primary cultured hepatocytes. J Nutri Sci Vitaminol (Tokyo). 2003 Dec;49(6):442-6.

Supplement Facts

Serving Size 1 softgel

Servings Per Container 60

Amount Per Serving



Calories from fat


Total Fat

1.3 g

Saturated fat

0.25 g

Monounsaturated fat

0.25 g

Polyunsaturated fat

0.8 g

Borage seed oil (Borago officinalis) gamma-linolenic acid (GLA) 285 mg

1300 mg

Sesame seed (Sesamum indicum) lignan extract [standardized to 60% sesamin (6 mg)]

10 mg

Other ingredients: magnesium stearate, gelatin and water.

The borage oil in Mega GLA is cold pressed, and is free of any pesticides and herbicides. This is a natural product and the amount of GLA can vary, but is never less than 285 mg per capsule.*

Dosage and Use

Take one softgel one to two times daily or as recommended by a healthcare practitioner.


Up to five softgels can be taken daily.


This product is best utilized when taken with food.


This product should not be used by individuals who have an allergy to sesame.


Keep out of reach of children.


Do not exceed recommended dose.


Do not purchase if outer seal is broken or damaged.

- If you have a bad reaction to product discontinue use immediately.

When using nutritional supplements, please inform your physician if your are undergoing treatment for a medical condition or if you are pregnant or lactating.

Product photo may not exactly match the product offered for sale. Please refer to the product description.