CR Mimetic
Longevity Formulamimics
the anti-aging effects of calorie restrictionand triggers
youthful gene expression. This comprehensive formula provides a
powerful blend ofsixphytonutrients, includingresveratrol,pterostilbene,quercetin,grape seed
polyphenols,black tea extract,
andfisetin,
a natural fruit antioxidant. All these phytonutrients have been shown
to generate many of the same effects in the body as caloric
restriction, without significant dietary modification. In particular,
they help mimic caloric restriction’s favorable impact ongenesthat influence the
aging process. Get broad-spectrum support for youthful gene expression
from scientifically validated phytonutrients in this comprehensive
formulation.
Benefits at a Glance
Mimic the anti-aging effects
of calorie restriction
Trigger youthful gene
expression
Favorably impact genes that
influence the aging process
Powerful blend of six
anti-aging nutrients
Trigger Youthful
Gene Expression
Life
Extension® has gone to extraordinary lengths to identify those
compounds that simulate calorie restriction’s ability to trigger
youthful gene expression— the process by which genes transmit signals
that slow certain aspects of aging. In 2003, we introduced standardized
extract ofresveratrol.
In
2009, we introduced the “other” resveratrol,pterostilbene, a
compound whose effects were found to work in synergy with resveratrol
to activate your “longevity genes.”
We’ve
combined six known calorie restriction mimetics —trans-resveratrol,
trans-pterostilbene, quercetin, grape seed polyphenols, black tea
extract, and fisetin — in one, high-potency formula.
The Original 5 –
Powerful Phytonutrients for Living Longer
Trans-resveratrolis the form of resveratrol
used in scientific studies documenting remarkable longevity enhancing
effects. You would have to drink many bottles of red wine to obtain a
fraction of thetrans-resveratrol (250 mg)
found in CR Mimetic Longevity Formula.
Trans-pterostilbene directly
activates genes“downstream”from the sites of
resveratrol’s action, providing a powerfulcomplementary stimulusto resveratrol’s
ability to induceyouthfulgene expression. You
would have to eat 135 cups of blueberries to obtain the amount oftrans-pterostilbene that is
contained in CR Mimetic Longevity Formula.
Quercetin
inhibits the actions of enzymes in the liver from rapidly breaking down
resveratrol in the bloodstream, thus enabling resveratrol to remain
active longer in the body.
Grape
seed extract provides proanthocyanidins that have multiple health
benefits and work together with resveratrol to trigger favorablegene expressionchanges. Theaflavins from
black tea inhibit the pro-inflammatory transcription factor NF-kB and stimulate the longevity
factor Forkhead box 1 (FOXO1) in invertebrate and mammalian cells.You would have to drink 12
six-ounce cups of black tea each day to obtain the amount of
theaflavins contained in CR Mimetic Longevity Formula.
The Sixth CR
Mimetic Discovered –Fisetin!
This
innovative formulation features the little-known flavonoidfisetin(which is most abundantly
found in strawberries).It is the sixth compound
shown to simulate a youthful gene expression pattern similar to calorie
restrictionwithout
significant dietary modification.
Fisetin
may also enhance the effects of resveratrol.Researchers have uncovered
compelling evidence of fisetin’s ability tostabilizeresveratrol by shielding it
from metabolic breakdown14…
thus extending its effects.
Fisetin
has been shown to have the power to “switch on” powerful cell-signaling
molecules that support youthful gene expression, DNA protection, and
healthy cellular function.15Fisetin also supports aging
neurons in the presence of oxidative stress.
And
each serving of CR Mimetic Longevity Formula contains fisetin in an
amount equivalent to 2 cups of strawberries, helping to further emulate
calorie restriction’s favorable influence on your longevity genes.
Get the Longevity
Benefits of Calorie Restriction without Restricting Calories
This
unique formula provides cutting-edge broad-spectrum support for
youthful gene expression from scientifically validated phytonutrients.
Just two capsules a day of CR Mimetic Longevity Formula mimics the
aging benefits of calorie restriction by triggering youthful gene
expression — without restricting calories!
This supplement
should be taken in conjunction with a healthy diet and regular exercise
program. Individual results are not guaranteed and results may vary.
Supplement
Facts
Serving size 2
vegetarian capsules
Servings per
container 30
Amount per serving
Trans-Resveratrol [from
Japanese knotweed extract (root)]
250 mg
Trans-Pterostilbene (from
pTeroPure®)
3 mg
Quercetin (as
quercetin dihydrate)
150 mg
Masquelier’s®Original OPCs [single and
condensed (2-5 units) of flavanols & polyphenols from grape seeds]
Other ingredients:
vegetable cellulose (capsule), microcrystalline cellulose, stearic
acid, silica.
Non-GMO
pTeroPure®
is a registered trademark of ChromaDex, Inc.
MASQUELIER’s® is a registered trademark of International Nutrition
Company BV (INC), Loosdrecht, The Netherlands.
Dosage and Use
Take two (2) capsules
daily with or without food, or as recommended by a healthcare
practitioner.
Can be taken together or
in divided doses.
Caution
Consult with your doctor
before using this product if you have a bleeding disorder, or if you
are taking anti-coagulant, anti-platelet, or diabetic medications.
Warnings
KEEP OUT OF REACH OF
CHILDREN
DO NOT EXCEED
RECOMMENDED DOSE
Do not purchase if outer
seal is broken or damaged.
When using nutritional
supplements, please consult with your physician if you are undergoing
treatment for a medical condition or if you are pregnant or lactating.